Which phase of healing involves the formation of scar tissue?

The formation of scar tissue primarily occurs during the proliferation phase of healing. This phase involves the migration of cells to the site of injury, where they work to rebuild the tissue structure. Fibroblasts, a type of cell that plays a crucial role in wound healing, produce collagen and other extracellular matrix components that form the basis of scar tissue.

As the body rebuilds the damaged area, new blood vessels also develop to supply nutrients and oxygen, facilitating the healing process. Scar tissue is typically less flexible and lacks the same quality as the original tissue, but it is essential for closing wounds and providing structural stability to the area.

The proliferation phase is critical because it sets the stage for further healing, with the scar tissue eventually being refined and remodeled in subsequent phases, leading to improved strength and flexibility over time. This remodeling phase is where further adjustments to the scar occur, but the initial formation happens during the proliferation phase.